Clinical psychiatrist and the daughter of SPECTRE operative Mr. White (Jesper Christensen), portrayed by Léa Seydoux in Spectre and No Time to Die. Poisoned by his employer, the mysterious Franz Oberhauser (Christoph Waltz), a dying Mr. White exacts a promise from James Bond (Daniel Craig) to protect his daughter from suffering a similar fate. In return, he tells Bond that Madeleine can lead him to Oberhauser.

Bond, indeed, rescues Madeleine from Mr. Hinx (Dave Bautista) and his murderous henchmen. Together they head for the L’Américain hotel in Tangier, where they discover White’s secret room and further clues that lead them into the desert and a confrontation with Oberhauser—a.k.a. SPECTRE head Ernst Stavro Blofeld.